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Security Vulnerability in Adobe Acrobat (and Reader)
I'm wondering too.
By the way, if you have BOTH Acrobat and Reader installed you'll want to change this setting in both of them.
You can find more information about this in the link above, or in this article.
UPDATE: There are active exploits for this in the wild. A patch from Adobe is forthcoming but as of this writing not yet available. More information from Network World here:
You can reach Ben M. Schorr at email@example.com or by phone at 808-782-6306.